As a supplement, we recommend starting at the recommended two capsule per day serving size of 1000 mg, taken with or without food. Inositol is often taken at much higher doses than this and has been studied at dosages up to 12 grams per day. If taking a higher dosage of Inositol that the recommended dosage, we recommend consulting with your physician and arriving at a dose you are both comfortable with as side effects are more likely at higher doses.